Free radicals and the heart.
作者： N. Kaul , N. Siveski-Iliskovic , M. Hill , J. Slezak , P.K. Singal
DOI: 10.1016/1056-8719(93)90008-3
关键词:
摘要: Abstract Because of the molecular configuration, most free radicals are highly reactive and can cause cell injury. Protective mechanisms have evolved to provide defense against freeradical Any time these systems overwhelmed, such as during disease states, dysfunction may occur. In this review we discuss cellular sources well significance radicals, oxidative stress, antioxidants. A probable role stress in various cardiac pathologies has been also analyzed. Although some methods for detection cited, better study quantity subcellular distribution needed order understand fully both health disease.
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sci-hub.se 参考文章(163)
H. Fliss, M. Masika, D. W. Eley, B. Korecky, Oxygen Radical Mediated Protein Oxidation in Heart Oxygen Radicals in the Pathophysiology of Heart Disease. pp. 71- 90 ,(1988) , 10.1007/978-1-4613-1743-2_6
M. L. Hess, T. D. Greenfield, N. H. Manson, Eiichiro Okabe, The Role of Oxygen Free Radicals during the Course of Myocardial Ischemia/Reperfusion Injury: An Analysis and Critique Oxygen Radicals in the Pathophysiology of Heart Disease. pp. 111- 122 ,(1988) , 10.1007/978-1-4613-1743-2_8
Rendeková, Verchovodko P, Cornák, Luknárová O, Barta E, Pechán I, Protective effect of alpha-tocopherol and L-ascorbic acid against the ischemic-reperfusion injury in patients during open-heart surgery. Bratislavské lekárske listy. ,vol. 92, pp. 174- ,(1991)
Slezak J, Tribulova N, Ravingerova T, Singal Pk, Myocardial heterogeneity and regional variations in response to injury. Laboratory Investigation. ,vol. 67, pp. 322- 330 ,(1992)
J. Lunec, D. G. Wickens, T. L. Graff, T. L. Dormandy, Copper, Free Radicals and Rheumatoid Arthritis Humana Press. pp. 231- 242 ,(1982) , 10.1007/978-1-4612-5829-2_23
S J Weiss, Oxygen, ischemia and inflammation. Acta Physiologica Scandinavica. ,vol. 548, pp. 9- 37 ,(1986)
I J Kopin, Catecholamine metabolism: basic aspects and clinical significance. Pharmacological Reviews. ,vol. 37, pp. 333- 364 ,(1985)
R. Bolli, B. S. Patel, W. X. Zhu, P. G. O'Neill, C. J. Hartley, M. L. Charlat, R. Roberts, The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction American Journal of Physiology-heart and Circulatory Physiology. ,vol. 253, ,(1987) , 10.1152/AJPHEART.1987.253.6.H1372
David V. Godin, Saleh A. Wohaieb, Reactive Oxygen Radical Processes in Diabetes Oxygen Radicals in the Pathophysiology of Heart Disease. pp. 303- 322 ,(1988) , 10.1007/978-1-4613-1743-2_20
E. D. Wills, Lipid peroxide formation in microsomes. The role of non-haem iron. Biochemical Journal. ,vol. 113, pp. 325- 332 ,(1969) , 10.1042/BJ1130325