Bullous Pemphigoid and Amyotrophic Lateral Sclerosis
作者： Olivier Chosidow , Valérie Doppler , Gilbert Bensimon , Pascal Joly , François Salachas
DOI: 10.1001/ARCHDERM.136.4.521
关键词:
摘要: Background Bullous pemphigoid (BP) occurs in many patients with multiple sclerosis. Isolated cases of BP other neurological disorders further support a pathogenic association between cutaneous and diseases. Any description amyotrophic lateral sclerosis is lacking. Observations We studied French population 168 typical Among these, 3 had clinical histological features BP. The mean age the was 54 years. None known to have autoimmune disorders. Results immunoblot analysis disclosed both anti-BP antigen 1 2 antibodies. Conclusions seems be unexpectedly associated On basis presented herein, we discuss epidemiological significance possible interrelation neurofilaments pathogenesis
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