A Symmetry rule for the Circular Dichroism of reducing sugars, and the proportion of Carbonyl forms in Aqueous solutions thereof

摘要: Abstract From the circular dichroisrm spectra of 23 aldoses and 10 ketoses in aqueous solution, a symmetry rule was derived relating sign n- band carbonyl form to absolute configuration sugar. The is positive when adjacent chiral center (S), it negative (R). also holds for aldehydo- keto-sugar peracetates, y-lactones substituted with oxygen-containing groups. magnitude mean, molar, dichroic-extinction coefficient pure forms estimated from published c.d. data on peracetates related compounds, which permitted estimation proportion equilibrium mixture each D-Glucose had smallest concentration, 0.002% at 20°, agreement an earlier, polarographic value. relationship between content sugar structure discussed.