Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study
作者： Telma Blanca Lombardo Bedran , Rosemary Adriana C. Marcantonio , Rubens Spin Neto , Marcia Pinto Alves Mayer , Daniel Grenier
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摘要: Background: Although previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, occurrence this pathogen diseased periodontal sites without lesions has been poorly investigated. Objective: The aims study were to quantify P. patients evaluate potential correlation gingivalis and Tannerella forsythia , ability treatment reduce these pathogens. Design: Patients generalized selected by recording clinical attachment level (CAL), probing depth (PD), bleeding on (BOP). Subgingival samples from 30 nonadjacent (CAL≥5 mm, PD between 5 7 mm positive BOP) healthy (PD≤3 negative collected subjected microbial analysis quantitative polymerase chain reaction (qPCR). variables age, PD, CAL BOP all individuals analyzed using paired t-test (GrapPad Prism5®). Data bacteria quantification a normality test (D’Agostino-Pearson Test). For bacterial analysis, Spearman was used. Results: Our results showed that had significantly higher levels compared sites, similar obtained for T. . numbers species reduced after mechanical treatment. correlated group. Conclusion: suggest there is high prevalence effective at reducing pathogens studied. Keywords: periodontitis; reaction; porphyromonas endodontalis; gingivalis; (Published: January 2012) Citation: Journal Oral Microbiology 2012, 4 : 10123 - DOI: 10.3402/jom.v4i0.10123
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