Cancer survival in five continents: a worldwide population-based study (CONCORD)

摘要: Summary Background Cancer survival varies widely between countries. The CONCORD study provides estimates for 1·9 million adults (aged 15–99 years) diagnosed with a first, primary, invasive cancer of the breast (women), colon, rectum, or prostate during 1990–94 and followed up to 1999, by use individual tumour records from 101 population-based registries in 31 countries on five continents. This is, our knowledge, first worldwide analysis survival, standard quality-control procedures identical analytic methods all datasets. Methods To compensate wide international differences general population (background) mortality age, sex, country, region, calendar period, (in USA) ethnic origin, we estimated relative ratio noted patients cancer, that would have been expected had they subject only background rates. 2800 life tables were constructed. Survival also adjusted age structure populations cancer. Findings Global variation was very wide. 5-year breast, colorectal, generally higher North America, Australia, Japan, northern, western, southern Europe, lower Algeria, Brazil, eastern Europe. has provided opportunity estimate 11 states USA covered National Program Registries (NPCR), covers 42% US population, four-fold more than previously available. black men women systematically substantially white 16 six metropolitan areas included. Relative ethnicities combined 2–4% NPCR Surveillance Epidemiology End Results (SEER) Program. Age-standardised appropriate race-specific state-specific 2% 5% census-derived national used SEER These coverage analytical method both contributed deficit Europe USA, which data available until now. Interpretation Until now, direct comparisons high-income low-income not information here might therefore be useful stimulus change. findings should eventually facilitate joint assessment trends incidence, as indicators control. Funding Centers Disease Control Prevention (Atlanta, GA, USA), Department Health (London, UK), Research UK UK).