Serum progesterone concentrations on the day of HCG administration cannot predict pregnancy in assisted reproduction cycles
作者： Francisca Martínez , Buenaventura Coroleu , Elisabeth Clua , Rosa Tur , Rosario Buxaderas
DOI: 10.1016/S1472-6483(10)60514-7
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摘要: Abstract The effect of subtle rises progesterone in the late follicular phase cycles ovarian stimulation with gonadotrophin-releasing hormone (GnRH) agonists on pregnancy outcome is controversial. This study used receiver-operating characteristic (ROC) analysis to gain further insight into predictive value serum concentrations day human chorionic gonadotrophin (HCG) injection normally responding patients receiving long protocol GnRH agonist (group L; n = 218) and low responders short (‘flare-up') S; 159). ROC showed that concentration HCG was not indicative conception non-conception whole population studied, group L or S. To assess potential impact ‘high' circulating administration rates outcome, threshold ( 197) ‘normal' N; 180) applied. No significant differences were found respect miscarriage between these two groups. Serum therefore cannot predict assisted reproduction using gonadotrophins.
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