作者: Elsa-Grace V. Giardina , Lynne L. Johnson , Joseph Vita , J.Thomas Bigger , Rachel F. Brem
DOI: 10.1016/0002-8703(85)90240-6
关键词:
摘要: Abstract The effect of imipramine or nortriptyline on left ventricular function and orthostatic blood pressure was evaluated in 20 nondepressed cardiac patients treated for premature depolarizations (VPDs). Drug administered by mouth dose ranging used, 1 mg/kg/day (imipramine) 0.5 (nortriptyline), increased after four doses six (nortriptyline) until >80% suppression VPDs adverse effects occurred a maximum 5 3.5 given. Fourteen (70%) had VPD suppression, five p 30 mm Hg. There not significant relationship between dose, drug concentration, functional class change systolic but there age (