Hypertonic saline reduces lipopolysaccharide-induced mouse brain edema through inhibiting aquaporin 4 expression
作者： Cao C , Yu X , Liao Z , Zhu N , Huo H
DOI: 10.1186/CC11670
关键词:
摘要: Introduction Three percent sodium chloride (NaCl) treatment has been shown to reduce brain edema and inhibited aquaporin 4 (AQP4) expression in bacterial meningitis induced by Escherichia coli. Lipopolysaccharide (LPS) is the main pathogenic component of E. We aimed explore effect 3% NaCl mouse LPS, as well elucidate potential mechanisms action.
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