Molecular Epidemiology of Ascaris Infection Among Pigs in Iowa

作者: Jeba Jesudoss Chelladurai , Kaitlyn Murphy , Tymbrie Snobl , Christopher Bader , Cody West

DOI: 10.1093/INFDIS/JIW507

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摘要: Ascaris is a large roundworm parasite that infects humans and pigs throughout the world. Molecular markers have been used to study transmission in Ascaris-endemic -nonendemic regions of In United States, ascariasis still persists commercial swine has designated neglected disease poverty humans. However, relatively few data are available for evaluation zoonotic transmission. present study, we obtained adult worms from abattoirs characterized each worm on basis gene encoding nuclear internal transcribed sequence (ITS) mitochondrial cox1 Restriction fragment-length polymorphism analysis ITS revealed swine, human, hybrid genotypes. sequences were compared all complete GenBank, haplotype demonstrated 92 haplotypes worldwide. Sequences parasites this represented 10 haplotypes, including 6 new not previously described. Our results indicate anthropozoonotic occurred past, resulting presence human genotypes supporting further investigation States.

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