Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma.

作者: Bernard J. Park , Charles K. Brown , Yun Hu , H. Richard Alexander , Jozsef Horti

DOI: 10.1089/10430349950018292

关键词:

摘要: The lineage-specific human tyrosinase promoter has been used to successfully target gene expression at the transcriptional level melanoma cells. promoter, alone and in combination...

参考文章(43)
Richard G. Vile, Ian R. Hart, In Vitro and in Vivo Targeting of Gene Expression to Melanoma Cells Cancer Research. ,vol. 53, pp. 962- 967 ,(1993)
Eric R. Schuur, Daniel R. Henderson, Ronald Rodriguez, Jonathan W. Simons, Gail A. Henderson, Ho Yeong Lim, Prostate Attenuated Replication Competent Adenovirus (ARCA) CN706: A Selective Cytotoxic for Prostate-specific Antigen-positive Prostate Cancer Cells Cancer Research. ,vol. 57, pp. 2559- 2563 ,(1997)
William M. Siders, Robert G. Fenton, Patrick J. Halloran, Transcriptional Targeting of Recombinant Adenoviruses to Human and Murine Melanoma Cells Cancer Research. ,vol. 56, pp. 5638- 5646 ,(1996)
Taiki Tamaoki, Hidekazu Nakabayashi, Toshi Kotani, Gary McGarrity, Paul Hallenbeck, W. French Anderson, Shuichi Kaneko, Yawen L. Chiang, Adenovirus-mediated Gene Therapy of Hepatocellular Carcinoma Using Cancer-specific Gene Expression Cancer Research. ,vol. 55, pp. 5283- 5287 ,(1995)
Shigenobu Nagataki, Taiki Tamaoki, Hiroshi Shiku, Nobuko Ishii, Yuji Kato, Kazuhiko Nakao, Keisuke Nakata, Ken Murata, Masatoshi Fujita, Akio Ido, Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter Cancer Research. ,vol. 55, pp. 3105- 3109 ,(1995)
Cynthia A. Richards, Brian E. Huber, Vincent C. Knick, Elizabeth A. Austin, Steven S. Good, Stephen Tibbels, In Vivo Antitumor Activity of 5-Fluorocytosine on Human Colorectal Carcinoma Cells Genetically Modified to Express Cytosine Deaminase Cancer Research. ,vol. 53, pp. 4619- 4626 ,(1993)
K Shibata, Y Muraosa, Y Tomita, H Tagami, S Shibahara, Identification of a cis-acting element that enhances the pigment cell-specific expression of the human tyrosinase gene. Journal of Biological Chemistry. ,vol. 267, pp. 20584- 20588 ,(1992) , 10.1016/S0021-9258(19)36726-2
Jens Dannull, Randhir Kaboo, Jean B. deKernion, Arie S. Belldegrun, Cho-Lea Tso, Kiarash Michel, Yiming Xie, Shen Pang, Identification of a Positive Regulatory Element Responsible for Tissue-specific Expression of Prostate-specific Antigen Cancer Research. ,vol. 57, pp. 495- 499 ,(1997)
K Yasumoto, K Yokoyama, K Shibata, Y Tomita, S Shibahara, Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene. Molecular and Cellular Biology. ,vol. 14, pp. 8058- 8070 ,(1994) , 10.1128/MCB.14.12.8058