Impact of age on laryngopharyngeal reflux disease presentation: a multi-center prospective study

摘要: The objective is to assess the differences in severity of symptoms, signs, voice quality, and quality life before after treatment according age suspected laryngopharyngeal reflux (LPR) patients. design used this paper prospective multi-center study. Eighty clinically diagnosed LPR patients with a finding score (RFS) >7 symptom index (RSI) >13 were treated pantoprazole diet recommendations for 3 months. Patients subdivided into three groups their age: group 1 (18-39 years, N = 21), 2 (40-59 years, N = 31), (≥60 years, N = 28). RSI, RFS, Voice Handicap Index (VHI), Short Form 36 questionnaire (SF36), aerodynamic, acoustic measurements evaluated at baseline treatment. response empiric was also assessed. Significant improvements VHI found all patient groups. elderly showed significantly lower RSI than younger subjects (p = 0.035) without RFS difference among At baseline, SF36 better respect social functioning (p = 0.049). 3-month follow-up, we significant improvement parameters only (group 2). rate resistant higher (42.9 versus 28.6%). Age appears reduce subjective perception, leading uncured utilization as an indicator effectiveness seems less useful subjects, probably due overlap between aging LPR.