Gut sweet taste receptors and their role in metabolism.

摘要: Obesity is caused by an imbalance between food intake and energy expenditure. In recent decades the gastrointestinal tract has received growing attention as a control parameter for regulation of appetite intake, however regulatory circuits their interactions are complex. The basic understanding on role gut starts with notion ‘we what we eat'. Food enters tract, which then triggers specific mechanisms or sensing machinery that respond to components food. Enteroendocrine cells in small intestine anatomical basis machinery, act neural intestinal satiation peptide-secreting cells. These express chemosensory receptors luminal stimuli. each mechanism might be involved process eating provides assessment potential fight against obesity. This review discusses function sweet taste receptor T1R2/T1R3 compounds, well its peptide secretion glucose metabolism.