Clinical manifestations of rotavirus infection in the neonatal intensive care unit.

摘要: Objectives This report describes clinical signs of rotavirus infection (RVI) among neonates admitted to a neonatal intensive care unit (NICU), compares these between term and preterm assesses the seasonal distribution RVI in NICU with that community. Methods After an initial prevalence study 28 days, prospective longitudinal was conducted. During next 48 months from December 1, 1991 November 30, 1995, patients were evaluated daily for pre-defined deviations their baseline gastrointestinal status. Fecal specimens who fulfilled entry criteria tested by monoclonal antibody-based enzyme immunoassay immunoelectron microscopy. Demographic outcome data collected. In addition assessing community collected during this period. Results The 18.4%. Of 194 included study, 95 had RVI. Neonates differed those without respect frequent stooling (P = 0.0005), higher percentage bloody mucoid stools 0.003) watery 0.023). odds three outcomes approximately 2.5 times than Among advanced necrotizing enterocolitis occurred at same rate (15%) Comparisons showed 0.0001) more often neonates, whereas 0.001), abdominal distention 0.03) intestinal dilatation 0.016) common neonates. paralleled its Conclusion appears prevalent setting. An absence neonate should not preclude consideration when evaluating spectrum differs infants.