Contrasting properties of NMDA-dependent and NMDA-independent forms of LTP in hippocampal pyramidal cells
作者： Roger A. Nicoll , Robert A. Zalutsky
DOI: 10.1007/978-3-642-78102-5_17
关键词:
摘要: Repetitive activation of a number different types synapses evokes persistent enhancement in synaptic strength. This use dependent is referred to as long-term potentiation (LTP) and thought underlie certain forms learning. The properties LTP elicited pathways or even the same pathway under conditions can differ substantially. evoked excitatory dentate gyrus CA1 region hippocampus has been studied most detail known require N-methyl-D-aspartate (NMDA) glutamate receptor subtype. Ca++ enters cell through NMDA receptors be responsible for triggering LTP.
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