Molecular basis for sunitinib efficacy and future clinical development
作者： Sandrine Faivre , George Demetri , William Sargent , Eric Raymond
DOI: 10.1038/NRD2380
关键词:
摘要: … This article reviews the effects of sunitinib on tumour angiogenesis, discusses the tumour … by sunitinib and the translational research that might be required to optimize the use of sunitinib…
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Julie M. Cherrington, Laurie M. Strawn, Laura K. Shawver, New paradigms for the treatment of cancer: The role of anti-angiogenesis agents Advances in Cancer Research. ,vol. 79, pp. 1- 38 ,(2000) , 10.1016/S0065-230X(00)79001-4
Claire Lewis, Craig Murdoch, Macrophage Responses to Hypoxia: Implications for Tumor Progression and Anti-Cancer Therapies American Journal of Pathology. ,vol. 167, pp. 627- 635 ,(2005) , 10.1016/S0002-9440(10)62038-X
Farshid Firoozbakht, Tad Kornaga, Laura E. Benjamin, Avner Adini, Placental Growth Factor Is a Survival Factor for Tumor Endothelial Cells and Macrophages Cancer Research. ,vol. 62, pp. 2749- 2752 ,(2002)
C. Bello, S. E. Deprimo, C. Friece, J. Smeraglia, L. Sherman, L. Tye, C. Baum, N. J. Meropol, H. Lenz, M. H. Kulke, Analysis of circulating biomarkers of sunitinib malate in patients with unresectable neuroendocrine tumors (NET): VEGF, IL-8, and soluble VEGF receptors 2 and 3 Journal of Clinical Oncology. ,vol. 24, pp. 4045- 4045 ,(2006) , 10.1200/JCO.2006.24.18_SUPPL.4045
Eva Sapi, The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Experimental Biology and Medicine. ,vol. 229, pp. 1- 11 ,(2004) , 10.1177/153537020422900101
Koichi Hattori, Beate Heissig, Yan Wu, Sergio Dias, Rafael Tejada, Barbara Ferris, Daniel J Hicklin, Zhenping Zhu, Peter Bohlen, Larry Witte, Jan Hendrikx, Neil R Hackett, Ronald G Crystal, Malcolm AS Moore, Zena Werb, David Lyden, Shahin Rafii, None, Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1 + stem cells from bone-marrow microenvironment Nature Medicine. ,vol. 8, pp. 841- 849 ,(2002) , 10.1038/NM740
M.D. Michaelson, T.E. Hutson, P. Tomczak, R.M. Bukowski, O. Rixe, S. Negrier, S.T. Kim, I. Chen, R.A. Figlin, R.J. Motzer, 4509 POSTER Sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC): updated efficacy and safety results and further analysis of prognostic factors Ejc Supplements. ,vol. 5, pp. 301- ,(2007) , 10.1016/S1359-6349(07)71140-0
Lesley J. Murray, Tinya J. Abrams, Kelly R. Long, Theresa J. Ngai, Lisa M. Olson, Weiru Hong, Paul K. Keast, Jacqueline A. Brassard, Anne Marie O'Farrell, Julie M. Cherrington, Nancy K. Pryer, SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clinical & Experimental Metastasis. ,vol. 20, pp. 757- 766 ,(2003) , 10.1023/B:CLIN.0000006873.65590.68
Oriol Casanovas, Daniel J. Hicklin, Gabriele Bergers, Douglas Hanahan, Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors Cancer Cell. ,vol. 8, pp. 299- 309 ,(2005) , 10.1016/J.CCR.2005.09.005
Louis M. Sherwood, Edith E. Parris, Judah Folkman, Tumor Angiogenesis: Therapeutic Implications New England Journal of Medicine. ,vol. 285, pp. 1182- 1186 ,(1971) , 10.1056/NEJM197111182852108