Calcification. XXIV. Mineralization of collagen and other fibers.

摘要: Abstract Purified tail tendon and skin acid-soluble collagens mineralize equally well in vitro when precipitated with chondroitin sulfate. Crude preparations of collagen poorly, compared to collagen. Finely cut rat showed appreciable calcifiability , but fresh calcified only a slight extent. Fibrin, some experiments, and, small extent, surgical silk . Rat hair filter paper did not calcify Acid-insoluble (often referred as cross-linked) bovine Achilles' rachitic bone slices treated 0.5 M sodium citrate at pH 7.3 this was blocked by acidification or EDTA. Calcification cartilage takes place more rapid rate lower Ca × P product than that Some objections the concept mineralization are presented. It is concluded although represents an incomplete inadequate model for calcifying matrix vivo it does constitute mineralizing related bone.