Chapter 7 Reconstruction of cortical circuitry

作者: Monte A. Gates , Rosemary A. Fricker-Gates , Jeffrey D. Macklis

DOI: 10.1016/S0079-6123(00)27008-8

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摘要: Publisher Summary This chapter discusses the ongoing studies of neocortical transplantation for brain repair in their historical context, and provides background current from prior experiments. The describes ways which using have contributed to understanding development. Understanding factors that control neuronal development plasticity is critical goal reconstruction complex circuitry adult. Toward these ends, as proceed, it will be investigate molecular controls over growth, survival, differentiation, immature neurons during normal central nervous system (CNS) find harness this information reconstruct circuits degenerated or damaged adult cerebral cortex. future possibility replacing degenerating injured neocortex toward functional also discussed chapter.

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