Panax ginseng and Eleuthrococcus senticosus extracts--in vitro studies on binding to steroid receptors.
作者： P. T. PEARCE , I. ZOIS , K. N. WYNNE , J. W. FUNDER
DOI: 10.1507/ENDOCRJ1954.29.567
关键词:
摘要: We have examined the binding of 44% saponin from Panax ginseng, and extracts Eluthrococcus senticosus (Siberian ginseng) to classical steroid receptors in vitro. Both had demonstrable affinity for progestin, mineralocorticoid glucocorticoid receptors; Siberian ginseng also bound estrogen receptors. Highest was receptors, with an approximate Ki 8 x 10(-6) M ginseng. Such interactions may explain reported glucocorticoid-like effects vivo.
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