Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21

作者: Adam J. Fletcher , Donna L. Mallery , Ruth E. Watkinson , Claire F. Dickson , Leo C. James

DOI: 10.1073/PNAS.1507534112

关键词:

摘要: … 1) correlates with a dependence on these enzymes for ubiquitination of TRIM21 in cells. To test this, we sought evidence for ubiquitinated TRIM21 by expressing TRIM21 with an N-…

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