Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
作者： Donna L Mallery , Leo C James , William A McEwan , Jerry C H Tam , Ruth E Watkinson
DOI: 10.1038/NI.2548
关键词:
摘要: … the ubiquitously expressed cytosolic antibody receptor TRIM21. Here we found that recognition of intracellular antibodies by TRIM21 activated immune signaling. TRIM21 catalyzed the …
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