Epidemiology of Urban Canine Rabies, Santa Cruz, Bolivia, 1972–1997

摘要: We analyzed laboratory data from 1972 to 1997 Santa Cruz, Bolivia, determine risk factors for canine samples’ testing positive Rabies virus (RABV). Of 9,803 samples, 50.7% tested RABV; the number of cases and percentage has dropped significantly since 1978. A 5- 6-year cycle in rabies incidence was clearly apparent, though no seasonality noted. Male dogs had increased odds RABV (odds ratio [OR]=1.14), as did 1- 2-year-old (OR=1.73); younger older were at lower risk. Samples submitted poorer suburbs city more likely test (OR=1.71). Knowledge distribution endemic an urban area will help focus control measures a resource-poor environment. urope North America have successfully controlled domestic animals, leaving wildlife main reservoir concern (1,2). Nevertheless, remains serious public health hazard many developing countries, where dog bites continue be mode transmission disease humans. Throughout world, estimated 35,000 100,000 people year die (1,3). The also elicits fear communities, subsequent are drains on budgets (4,5). is particular problem larger cities less-developed with sprawling, impoverished high densities (3,6,7). Controlling populations seen cost-effective, long-term approach prevent human than reliance postexposure treatment (8). To achieve control, knowledge epidemiology long been recognized crucial (9). In South several areas eliminated through legislation, education, mass vaccination (10). Cities countries such however, lag behind efforts, large part because resources scarce, programs poorly focused. these situations, efforts must directed. settings needed assess danger health. 26 years diagnosis endemic. interpreted results light possible biases temporal trends general population. Materials Methods