Targeting pro-apoptotic trail receptors sensitizes HeLa cervical cancer cells to irradiation-induced apoptosis
作者： John H. Maduro , Elisabeth G.E. de Vries , Gert-Jan Meersma , Brigitte M.T. Hougardy , Ate G.J. van der Zee
DOI: 10.1016/J.IJROBP.2008.06.1902
关键词:
摘要: … irradiation sensitizes the HPV18-positive HeLa cervical cancer … This is the first report showing that in cervical cancer cells, … found in human cervical cancer. Our experiments illustrated …
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Brigitte M.T. Hougardy, John H. Maduro, Ate G.J. van der Zee, Derk Jan A. de Groot, Fiona A.J. van den Heuvel, Elisabeth G.E. de Vries, Steven de Jong, Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis. International Journal of Cancer. ,vol. 118, pp. 1892- 1900 ,(2006) , 10.1002/IJC.21580
Lianghua Bin, Jacqueline Thorburn, Lance R. Thomas, Peter E. Clark, Robin Humphreys, Andrew Thorburn, Tumor-derived Mutations in the TRAIL Receptor DR5 Inhibit TRAIL Signaling through the DR4 Receptor by Competing for Ligand Binding * Journal of Biological Chemistry. ,vol. 282, pp. 28189- 28194 ,(2007) , 10.1074/JBC.M704210200
A. M. Chinnaiyan, U. Prasad, S. Shankar, D. A. Hamstra, M. Shanaiah, T. L. Chenevert, B. D. Ross, A. Rehemtulla, Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 1754- 1759 ,(2000) , 10.1073/PNAS.030545097
Fred Bunz, Paul M. Hwang, Chris Torrance, Todd Waldman, Yonggang Zhang, Larry Dillehay, Jerry Williams, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Disruption of p53 in human cancer cells alters the responses to therapeutic agents Journal of Clinical Investigation. ,vol. 104, pp. 263- 269 ,(1999) , 10.1172/JCI6863
John A Green, John M Kirwan, Jayne F Tierney, Paul Symonds, Lydia Fresco, Mandy Collingwood, Christopher J Williams, Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis The Lancet. ,vol. 358, pp. 781- 786 ,(2001) , 10.1016/S0140-6736(01)05965-7
Baoxiang Guan, Ping Yue, Gary L. Clayman, Shi-Yong Sun, Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. Journal of Cellular Physiology. ,vol. 188, pp. 98- 105 ,(2001) , 10.1002/JCP.1101
Sharmila Shankar, Thiyam Ramsing Singh, Rakesh K. Srivastava, Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms. The Prostate. ,vol. 61, pp. 35- 49 ,(2004) , 10.1002/PROS.20069
U Ramp, E Caliskan, C Mahotka, A Krieg, S Heikaus, H E Gabbert, C D Gerharz, Apoptosis induction in renal cell carcinoma by TRAIL and γ-radiation is impaired by deficient caspase-9 cleavage British Journal of Cancer. ,vol. 88, pp. 1800- 1807 ,(2003) , 10.1038/SJ.BJC.6600984
Martin Scheffner, Noel J. Whitaker, Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system. Seminars in Cancer Biology. ,vol. 13, pp. 59- 67 ,(2003) , 10.1016/S1044-579X(02)00100-1
J. Michael Straughn, Patsy G. Oliver, Tong Zhou, Wenquan Wang, Ronald D. Alvarez, William E. Grizzle, Donald J. Buchsbaum, Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model Gynecologic Oncology. ,vol. 101, pp. 46- 54 ,(2006) , 10.1016/J.YGYNO.2005.09.053