Novel purine derivatives, method for preparing them, their application as medicinal products, pharmaceutical compositions and novel use

作者: Florence Bordon-Pallier , Jean-Luc Haesslein

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摘要: The invention relates to novel products of formula (I): in which: Y represents N, O, S, CHR3 or ═CR3 the dashed line representing a single double bond, R and R1 represent in particular H, Hal, OH, alkyl, alkoxy, cyano, NO 2 , NR4R5, trifluoromethyl, trifluoromethoxy, aryl, heteroaryl, —S(O)n-NR4R5 with n 0 2, acyl, —NH—CO-alkyl —NH—CO—NH-phenyl, R3 trifluoromethyl R2 R4, OR4, SR4 R4 cycloalkyl either R5 are chosen from values for form, heterocyclic radical which may contain O all these radicals being optionally substituted, isomeric forms salts, as medicinal products.

参考文章(1)
Nobuo Shimma, John Merrett, Isabel Najera, Wen-Rong Jiang, Takuo Tsukuda, Joseph Martin, Brian Dymock, Christopher Hobbs, Rene Devos, Anti-HCV nucleoside derivatives ,(2002)