Process for the preparation of methyltrifluoroacetate

作者: Louis Amiet

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摘要: A process for the preparation of methyltrifluoroacetate. Trifluoroacetic acid is contacted with an excess methanol and distilled to form a methyltrifluoroacetate/methanol azeotrope. The azeotrope trifluoroacetic in presence catalytic quantity strong followed by distillation obtain methyltrifluoroacetate can be used as synthesis intermediate pharmaceutical industry.

参考文章(3)
Shigeru Kamimori, Kiyoshi Fujita, Yukiyoshi Ito, Method for separation of an ester from a reaction mixture ,(1979)