Preparation method of trifluoroacetic acid ethyl ester
作者： Tao Lv , Weidong Xie , Wei Zhang
DOI:
关键词:
摘要: The invention relates to a preparation method of trifluoroacetic acid ethyl ester. comprises the following steps: evenly mixing an amine compound with ethanol in molar ratio (0.2-2):1, and then adding trichloroacetyl halide for reaction, wherein is (0.1-10):1, reaction temperature controlled at minus10-80 DEG C, time 0.5-10 hours; rectifying obtain In invention, used as binding agent, esterification carried out on ethanol, so that ester product directly obtained, thereby simplifying process not producing waste catalyst process, recycling byproducts solving environmental protection problem synthesis.
lens.org 参考文章(8)
Stefan Palsherm, Kerstin Eichholz, Francine Janssens, Max Braun, Johannes Eicher, Synthesis of low-fluoride organic compounds ,(1999)
Louis Amiet, Process for the preparation of methyltrifluoroacetate ,(1986)
Adriano Checchin, Giorgio Guglielmo, Saverio Grego, Process for the production of alkyl trifluoroacetates ,(1986)
Joachim Frehse, Kerstin Eichholz, Werner Rudolph, Wilhelm Pohlmeyer, Heinz-Rudi Feist, Max Braun, Process for producing carboxylic acid esters from carboxylic acid halides and alcohols ,(1994)
Kerstin Eichholz, Max Braun, Process for preparing esters ,(2002)
Zhou Weiyong, Zhou Huanjun, Perfluorotanyl acid esterification method, and its straight chain content analyzing method ,(2005)
Spengerle Lauri An, Zhong, Eberdsaken Ferrefdown, Andony Zushuhua, Process for preparation of trifluoroacetate and trifluoroacetic thioester ,(2001)