Oral care compositions and methods

摘要: Provided herein is a pharmaceutical or oral care product for treating preventing diseases that prepared with proteoglycan 4 (PRG4) as an active ingredient, the preparing method thereof and use in manufacturing medicaments products maintenance of health. PRG4 may have efficacy maintaining health disease. This secreted glycoprotein, which also called lubricin superficial zone protein, known to protect against frictional forces, cell adhesion protein deposition.