PCR analysis of the short tandem repeat (STR) system HUMVWA31. Allele and genotype frequencies in an Italian population sample.

摘要: A population study in a sample of 211 unrelated individuals from 2 cities North and Central Italy was carried out to investigate the short tandem repeat (STR) system HUMVWA31. Separation PCR- amplified DNA fragments performed by high-resolution horizontal denaturing polyacrylamide gel electrophoresis (PAGE) followed silver staining. The 7 common alleles were found, together with new smaller allele. Distribution observed genotypes did not deviate Hardy-Weinberg (H-W) equilibrium. power discrimination for this locus 0.93 chance exclusion 0.61. Good agreement found between allele frequencies Italian samples previous studies on Caucasians. results suggest that STR may be useful tool forensic investigations.