How to Screen

摘要: There are two clinically relevant questions when screening for portal hypertension: first, identification of patients at high risk significant hypertension (CSPH; defined by an hepatic venous pressure gradient (HVPG) ≥ 10 mmHg); second, esophageal varices (OV). Thanks to the improvements in noninvasive methods, most currently diagnosed a very initial stage cirrhosis, which CSPH and OV often absent. In this new scenario, large proportion HVPG measurements endoscopies may be unnecessary. Among available liver stiffness measurement using transient elastography (TE) has been extensively studied. The diagnostic performance TE predicting is not as good (AUROC 0.84 0.93, respectively). better ruling than out CSPH, whereas it OV. Strategies combining with platelet count spleen diameter could useful rule Finally, evidence accumulated so far indicates that methods cannot replace detailed evaluation upper GI endoscopy detecting However, settings where available, considered stratify CSPH. Similarly, strategies low having hypertension.