Genomics: Why Do "Similar" Patients Have Different Outcomes?
作者： Anush Oganesian , Debra A Schwinn , Maren Kleine-Brueggeney
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摘要: Genetic variety is an important factor in why supposedly “similar” patients react differently to drugs as well having different clinical outcomes. This review provides update on concepts modern genomic medicine, with emphasis clinically relevant study approaches like candidate gene and genome wide association studies, whole exon sequencing. The application of medicine its importance for rapid diagnosis disease causing agents, human tumor diagnosis/treatment cardiovascular are discussed. In addition direct applications, also play role elucidating new mechanisms disease.
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