Current applications of chromatographic methods for diagnosis and identification of potential biomarkers in cancer

摘要: Abstract Cancer is the leading cause of death worldwide. However, its early diagnosis and treatment improve survival. Due to asymptomatic properties almost all types cancer, some patients are misdiagnosed or disease overlooked. Despite availability well-known diagnostic tools, such as computed tomography, a wide range factors can limit successful application these techniques. The search for new alternative methods that would be able diagnose cancer definitively has aroused scientific interest. Many coupled techniques have been employed this purpose. Nevertheless, chromatographic platforms considered among most powerful which enabled metabolic profiling, and, result, identified biomarkers, essential in process. Rapid advances technologies made it possible introduce treatment, based on individual predisposition.