Prolactin and cortisol levels following acute alcohol challenges in women with and without a family history of alcoholism

摘要: In a pilot study 5 matched pairs of female social drinkers received both 0.56 g/kg alcohol and placebo in double-blind crossover design. Family history positive (FHP) women had biological fathers who met criteria for dependence, FHN no relatives these criteria. FHP BALs about 70 mg/dl 60 min after alcohol. subjects significantly lower prolactin levels 40, 80 following alcohol, but higher cortisol 130 150 No significant differences hormone occurred placebo.