Molecular devices based on reversible singlet oxygen binding in optical and photomedical applications

摘要: Polycyclic aromatic hydrocarbons are known to bind singlet oxygen with formation of endoperoxides, which can be released upon heating. This process is now capturing broad attention due its potential in photomedicine. Singlet generation decomposition endoperoxides at ambient temperatures represents an alternative classical photodynamic therapy (PDT), limited by hypoxia and reduced light penetration into cancer tissue. Moreover, endoperoxide chromophoric molecules allows for a straightforward modification the optical properties photoactive materials, e.g., shifting absorption/emission wavelength usually achieved chemical tuning. review provides summary latest advances this area research along discussion basic organic endoperoxides.