Nimotuzumab Enhances the Radiosensitivity of Cancer Cells In Vitro by Inhibiting Radiation-Induced DNA Damage Repair

作者: Yuan-yuan Qu , Song-liu Hu , Xiang-ying Xu , Rui-zhi Wang , Hong-yang Yu

DOI: 10.1371/JOURNAL.PONE.0070727

关键词:

摘要: Background Nimotuzumab is a humanized IgG1 monoclonal antibody specifically targeting EGFR. In this study, we aimed to investigate the molecular mechanisms of nimotuzumab in its effects enhancing cancer cell radiosensitivity.

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