Risk of lung cancer and residential radon in China: Pooled results of two studies

摘要: Studies of radon-exposed underground miners predict that residential radon is the second leading cause lung cancer mortality; however, case-control studies have not provided unambiguous evidence an association. Owing to small expected risks from and uncertainties in dosimetry, large or pooling multiple are needed fully evaluate effects. We pooled data 2 representing conducted China. The included 1050 cases 1996 controls. In data, odds ratios (OR) increased significantly with greater concentration. Based on a linear model, OR 95% confidence intervals (CI) at 100 Becquerel/cubic-meter (Bq/m(3)) was 1.33 (1.01,1.36). For subjects resident current home for 30 years more, Bq/m(3) 1.32 (1.07,1.91). Results across were consistent homogeneity. Estimates ORs similar extrapolations miner published North American Europe, suggesting long-term exposure concentrations found many homes increases risk.