Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways
作者： Jia Xiao , Chi Tat Ho , Emily C. Liong , Amin A. Nanji , Tung Ming Leung
DOI: 10.1007/S00394-013-0516-8
关键词:
摘要: … , fibrosis, and inflammation. This was accompanied by a significant expressional increase in markers for fibrosis, oxidative stress, and inflammation. TGF/SMAD, PI3 K/Akt/FoxO1, and NF…
hku.hk
springer.com
sci-hub.se 
researchgate.net 参考文章(52)
Arthur J McCullough, Pathophysiology of nonalcoholic steatohepatitis. Journal of Clinical Gastroenterology. ,vol. 40, ,(2006) , 10.1097/01.MCG.0000168645.86658.22
George L Tipoe, Amin A Nanji, Thomas Y H Lau, Man-Lung Fung, Emily C Liong, Tung-Ming Leung, Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice. Histology and Histopathology. ,vol. 26, pp. 201- 211 ,(2011) , 10.14670/HH-26.201
C L Mendenhall, H Takahashi, S W French, K Wong, Ito cell activation induced by chronic ethanol feeding in the presence of different dietary fats. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. ,vol. 1, pp. 357- 361 ,(1991)
Masahito Shimizu, I Bernard Weinstein, Hisataka Moriwaki, Andrew K Joe, Judith F Mckoy, Atsuko Deguchi, EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells. Journal of Experimental Therapeutics and Oncology. ,vol. 5, pp. 69- 78 ,(2005)
Amin A. Nanji, Kalle Jokelainen, Maryam Fotouhinia, Amir Rahemtulla, Peter Thomas, George L. Tipoe, Grace L. Su, Andrew J. Dannenberg, Increased severity of alcoholic liver injury in female rats: role of oxidative stress, endotoxin, and chemokines. American Journal of Physiology-gastrointestinal and Liver Physiology. ,vol. 281, ,(2001) , 10.1152/AJPGI.2001.281.6.G1348
George L. Tipoe, Amin A. Nanji, C.T. Ho, Thomas Y.H. Lau, Man-Lung Fung, Emily C. Liong, Tung-Ming Leung, Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD) Histology and Histopathology. ,vol. 24, pp. 1161- 1169 ,(2009) , 10.14670/HH-24.1161
Kiyotaka Nakagawa, Shiho Okuda, Teruo Miyazawa, Dose-dependent Incorporation of Tea Catechins, (–)-Epigallocatechin-3-gallate and (–)-Epigallocatechin, into Human Plasma Bioscience, Biotechnology, and Biochemistry. ,vol. 61, pp. 1981- 1985 ,(1997) , 10.1271/BBB.61.1981
Aileen dela Peña, Isabelle Leclercq, Jacqueline Field, Jacob George, Brett Jones, Geoffrey Farrell, NF-κB Activation, Rather Than TNF, Mediates Hepatic Inflammation in a Murine Dietary Model of Steatohepatitis Gastroenterology. ,vol. 129, pp. 1663- 1674 ,(2005) , 10.1053/J.GASTRO.2005.09.004
John P. Iredale, Hepatic stellate cell behavior during resolution of liver injury Seminars in Liver Disease. ,vol. 21, pp. 427- 436 ,(2001) , 10.1055/S-2001-17557
Hea Jin Park, Ji-Young Lee, Min-Yu Chung, Young-Ki Park, Allyson M. Bower, Sung I. Koo, Charles Giardina, Richard S. Bruno, Green Tea Extract Suppresses NFκB Activation and Inflammatory Responses in Diet-Induced Obese Rats with Nonalcoholic Steatohepatitis Journal of Nutrition. ,vol. 142, pp. 57- 63 ,(2012) , 10.3945/JN.111.148544