Chemopreventive and hepatoprotective effects of Epigallocatechin-gallate against hepatocellular carcinoma: role of heparan sulfate proteoglycans pathway.

作者: Mohamed M. Darweish , Ahmed Abbas , Mohamed A. Ebrahim , Mohammed M.H. Al-Gayyar

DOI: 10.1111/JPHP.12229

关键词:

摘要: … significant difference in caspase-3 activity in HCC rats treated with EGCG as well as increasing caspase-3 activity in HepG2. However, the inability of EGCG to elevate caspase-3 in the …

参考文章(59)
W. C. Powell, L. M. Matrisian, Complex Roles of Matrix Metalloproteinases in Tumor Progression Attempts to Understand Metastasis Formation I. ,vol. 213, pp. 1- 21 ,(1996) , 10.1007/978-3-642-61107-0_1
Mohammed MH Al-Gayyar, Mohammed A Abdelsaid, Suraporn Matragoon, Bindu A Pillai, Azza B El-Remessy, Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity British Journal of Pharmacology. ,vol. 164, pp. 170- 180 ,(2011) , 10.1111/J.1476-5381.2011.01336.X
Kathleen Lambaerts, Sarah A Wilcox-Adelman, Pascale Zimmermann, The signaling mechanisms of syndecan heparan sulfate proteoglycans Current Opinion in Cell Biology. ,vol. 21, pp. 662- 669 ,(2009) , 10.1016/J.CEB.2009.05.002
Masahito Shimizu, Yohei Shirakami, Hiroyasu Sakai, Hideharu Tatebe, Takayuki Nakagawa, Yukihiko Hara, I. Bernard Weinstein, Hisataka Moriwaki, EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells. Cancer Letters. ,vol. 262, pp. 10- 18 ,(2008) , 10.1016/J.CANLET.2007.11.026
Masahito Shimizu, Seiji Adachi, Muneyuki Masuda, Osamu Kozawa, Hisataka Moriwaki, Cancer chemoprevention with green tea catechins by targeting receptor tyrosine kinases. Molecular Nutrition & Food Research. ,vol. 55, pp. 832- 843 ,(2011) , 10.1002/MNFR.201000622
Piotr Stefaniuk, Present and future possibilities for early diagnosis of hepatocellular carcinoma World Journal of Gastroenterology. ,vol. 16, pp. 418- 424 ,(2010) , 10.3748/WJG.V16.I4.418
Jia Xiao, Chi Tat Ho, Emily C. Liong, Amin A. Nanji, Tung Ming Leung, Thomas Yue Huen Lau, Man Lung Fung, George L. Tipoe, Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways European Journal of Nutrition. ,vol. 53, pp. 187- 199 ,(2014) , 10.1007/S00394-013-0516-8
Chi‐Hung Huang, Shang‐Jie Tsai, Ying‐Jan Wang, Min‐Hsiung Pan, Jung‐Yie Kao, Tzong‐Der Way, None, EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells. Molecular Nutrition & Food Research. ,vol. 53, pp. 1156- 1165 ,(2009) , 10.1002/MNFR.200800592
Shuo Dong, Heparanase and hepatocellular carcinoma: Promoter or inhibitor? World Journal of Gastroenterology. ,vol. 16, pp. 306- 311 ,(2010) , 10.3748/WJG.V16.I3.306