Thyrotropin‐releasing factor: Distribution in neural and gastrointestinal tissues
作者： J. Leppäluoto , F. Koivusalo , R. Kraama
DOI: 10.1111/J.1748-1716.1978.TB06264.X
关键词:
摘要: Specimens of several rat tissues were purified with methanol extraction, gel filtration and cation exchange chromatography measured for thyrotropin-releasing factor (TRF) concentration by radioimmunoassay. TRF immunoreactivity neural (hypothalamus, spinal cord, medulla, cerebrum cerebellum) gastrointestinal (pancreas, stomach, duodenum colon) behaved as synthetic during the purification. This dual distribution suggests that TRF-secreting cells have their origin in embryonal neuroectoderm.
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