Serotoninergic Influences on Sexual Differentiation of the Rat Brain

作者: Barbara Jarzab , Klaus D. Döhler

DOI: 10.1016/S0079-6123(08)64431-3

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摘要: Publisher Summary A prime candidate for the mediation of sex hormone activity during sexual differentiation brain seems to be serotoninergic system. This chapter describes how serotonin may influence and discusses possible synthesis inhibitor pCPA on defeminization masculinization functions as well precursor L-tryptophan. The results show that postnatal inhibition neither stimulates nor inhibits effects testosterone propionate (TP) either pattern gonadotropin release or expression male female behavior. Postnatal stimulation synthesis, however, significantly inhibited behavior patterns, but it had no release. Increased availability in TP-treated rats, due administration L-tryptophan, interfered with both patterns. Thus, have a similar inhibitory effect organization patterns has activation adulthood. However, extent which interact remains uncertain.

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