Trisulfides in Proteins

作者: Rasmus Wedel Nielsen , Christine Tachibana , Niels Erik Hansen , Jakob Rahr Winther

DOI: 10.1089/ARS.2010.3677

关键词:

摘要: Abstract Trisulfides and other oligosulfides are widely distributed in the biological world. In plants, for example, garlic, trisulfides associated with potentially beneficial properties. However, an extra neutral sulfur atom covalently bound between two atoms of a pair cysteines is not common post-translational modification, number proteins which trisulfide has been unambiguously identified small. Nevertheless, we believe that its prevalence may be underestimated, particularly increasing evidence significant pools sulfides living tissues their possible roles cellular metabolism. This review focuses on examples known to contain bridge, gives overview chemistry formation, methods by it detected proteins. Antioxid. Redox Signal. 15, 67–75.

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