Medicinal plants and their isolated compounds showing anti-Trichomonas vaginalis- activity.
作者： Mozhgan Mehriardestani , Atousa Aliahmadi , Tayebeh Toliat , Roja Rahimi
DOI: 10.1016/J.BIOPHA.2017.01.149
关键词:
摘要: Trichomonas vaginalis is a major of non-viral sexually-transmitted infection and an important cause serious obstetrical gynecological complications. Treatment options for trichomoniasis are limited to nitroimidazole compounds. The increasing resistance allergic reactions recurrent make it essential identify develop new drugs against trichomoniasis. Medicinal plants source discovery medications. This review discusses the anti-trichomonas effects medicinal their chemical constituents find better this pathogenic protozoon. Electronic databases were searched collect all data from year 2000 through September 2015 in vitro, vivo clinical studies on effect T. vaginalis. A total 95 vitro identified. Only four human found review. Asteracea, Lamiaceae Myrtaceae families contained greatest number with activity. Persea americana, Ocimum basilicum Verbascum thapsus most efficacious Plant metabolites containing alkaloids, isoflavonoid glucosides, oils, lipids, saponins sesquiterpene lactones possess properties. Assessing structure-activity highly-potent phytochemicals suggested finding natural, semisynthetic synthetic Further necessary confirmation natural substances completion safety profiles.
em-consulte.com参考文章(81)
Mohammad Emaneini, Morovat Taherikalani, Parisa Asadollahi, Setareh Soroush, Mojtaba Taran, Khairollah Asadollahi, Sajjad Alizadeh, In vitro antimicrobial activity of Persian shallot (Allium hirtifolium). Roumanian archives of microbiology and immunology. ,vol. 71, pp. 70- ,(2012)
Manal J. Natto, Anthonius A. Eze, Harry P. de Koning, Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis Methods of Molecular Biology. ,vol. 1263, pp. 103- 110 ,(2015) , 10.1007/978-1-4939-2269-7_8
Agnieszka Beata Serwin, Marta Koper, Trichomoniasis--an important cofactor of human immunodeficiency virus infection. Przegla̧d epidemiologiczny. ,vol. 67, pp. 47- 134 ,(2013)
Qin YuanHua, Zheng LiLi, Dai XiaoDong, Tao Lin, Liu Xin, Ren YiXin, Cui Yu, Effect of Mosla chinensis Maxim on Trichomonas vaginalis in vitro. Journal of Dalian Medical University. ,vol. 31, pp. 282- 285 ,(2009)
Yan CHEN, You-Mei TANG, Su-Lan YU, Yu-Wei HAN, Jun-Ping KOU, Bao-Lin LIU, Bo-Yang YU, Advances in the pharmacological activities and mechanisms of diosgenin. Chinese Journal of Natural Medicines. ,vol. 13, pp. 578- 587 ,(2015) , 10.1016/S1875-5364(15)30053-4
Hadisa Tadayon, Elahm Farnia, Bahadoor Sarkari, Shahrbanoo Askarian, Mehrangiz Askarian, In Vitro anti-Trichomonas activity of Freula assafoetida and garlic extracts Journal of Gorgan University of Medical Sciences. ,vol. 11, pp. 13- 17 ,(2009)
Marcos Serpa, Marina Duarte, Niara Da Silva Medeiros, Mirian Salvador, Tiana Tasca, Caroline Dani, Cytotoxic activity of Vitis labrusca extract in cultures of Trichomonas vaginalis Sci. Med. (Online). ,vol. 24, pp. 73- 78 ,(2014) , 10.15448/1980-6108.2014.1.15834
N I Ramadan, F M Al Khadrawy, The in vitro effect of Assafoetida on Trichomonas vaginalis. Journal of the Egyptian Society of Parasitology. ,vol. 33, pp. 615- 630 ,(2003)
Khadijeh Abdali, Leila Jahed, Sedigheh Amooee, Mahnaz Zarshenas, Hamidreza Tabatabaee, Reza Bekhradi, Comparison of the Effect of Vaginal Zataria multiflora Cream and Oral Metronidazole Pill on Results of Treatments for Vaginal Infections including Trichomoniasis and Bacterial Vaginosis in Women of Reproductive Age. BioMed Research International. ,vol. 2015, pp. 683640- 683640 ,(2015) , 10.1155/2015/683640
Raquel B Giordani, Celso OR Junior, Jean P de Andrade, Jaume Bastida, Jose AS Zuanazzi, Tiana Tasca, Mauro V de Almeida, None, Lycorine Derivatives Against Trichomonas vaginalis Chemical Biology & Drug Design. ,vol. 80, pp. 129- 133 ,(2012) , 10.1111/J.1747-0285.2012.01333.X