Thrombosis in children with cardiac pathology: frequency of factor V Leiden and prothrombin G20210A mutations.

摘要: This study analyzed 28 thrombotic children with various cardiac disorders. They comprise 17% of a total 168 patients thrombosis from single center. Among the patients, 21 had congenital heart disease and 7 were diagnosed cardiomyopathy. The evaluated for acquired risk factors. In addition to disorders, two, three, or more factors present in 61% thrombosis. Two common mutations, namely factor V Leiden prothrombin G20210A found 6 (22%). Nine (32%) died infection, disease, cardiomyopathy, thrombosis, operation, combination these; two required surgical intervention. Following angiography, due necrosis, amputation right index finger lower extremity was performed on 1 patient. second patient's fingers be amputated resection bowel following operation coarctation aorta. indicates that cardiomyopathy are disorders may lead development majority develops within and/or its great vessels. predominant site thromboembolic symptoms is brain, including sinovenous