摘要: Recent studies have provided evidence that the human circadian timing system has an influence on respiration and respiratory control. Both sleep mechanisms combine to mediate rise in lower airway resistance nocturnal asthma. In rats, rhythms minute ventilation are present both wakefulness sleep, implying also control of breathing. The causes a increase chemoreflex threshold it is suggested this may propensity for apnea. This hypothesis supported by model analysis control, relevant published data reviewed. clinical implications putative contribution apnea potentially very significant, but scarce directions future research discussed.
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Richard L. Horner, Motor control of the pharyngeal musculature and implications for the pathogenesis of obstructive sleep apnea. Sleep. ,vol. 19, pp. 827- 853 ,(1996) , 10.1093/SLEEP/19.10.827
William C. Dement., Thomas Roth, Meir H. Kryger, Principles and Practice of Sleep Medicine ,(1989)
CA Czeisler, DJ Dijk, Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans The Journal of Neuroscience. ,vol. 15, pp. 3526- 3538 ,(1995) , 10.1523/JNEUROSCI.15-05-03526.1995
Eliot A. Phillipson, Glenn Bowes, Control of breathing during sleep Harefuah. ,vol. 105, pp. 317- 322 ,(2011) , 10.1002/CPHY.CP030219
Richard Stephenson, Ravi M. Mohan, James Duffin, Tim M. Jarsky, Circadian rhythms in the chemoreflex control of breathing American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 278, ,(2000) , 10.1152/AJPREGU.2000.278.1.R282
K. Krauchi, A. Wirz-Justice, Circadian rhythm of heat production, heart rate, and skin and core temperature under unmasking conditions in men American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 267, ,(1994) , 10.1152/AJPREGU.1994.267.3.R819
M. C. Moore-Ede, Physiology of the circadian timing system: predictive versus reactive homeostasis American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. ,vol. 250, pp. R737- R752 ,(1986) , 10.1152/AJPREGU.1986.250.5.R737
C. Czeisler, E Weitzman, M. Moore-Ede, J. Zimmerman, R. Knauer, Human sleep: its duration and organization depend on its circadian phase Science. ,vol. 210, pp. 1264- 1267 ,(1980) , 10.1126/SCIENCE.7434029
Giuseppe Piccione, Giovanni Caola, Jacopo P. Mortola, Day/night pattern of arterial blood gases in the cow Respiratory Physiology & Neurobiology. ,vol. 140, pp. 33- 41 ,(2004) , 10.1016/J.RESP.2003.11.008
T. Schäfer, Variability of vigilance and ventilation: studies on the control of respiration during sleep. Respiration Physiology. ,vol. 114, pp. 37- 48 ,(1998) , 10.1016/S0034-5687(98)00070-X