The PPARα Activator Fenofibrate Slows Down the Progression of the Left Ventricular Dysfunction in Porcine Tachycardia-Induced Cardiomyopathy

作者: Fran??ois Brigadeau , Patrick Gel?? , Maud Wibaux , Christelle Marqui?? , Fran??oise Martin-Nizard

DOI: 10.1097/FJC.0B013E3180544540

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摘要: Abstract:It has been reported that high intramyocardial peroxisome proliferator-activated receptor α (PPARα) stimulation or overexpression altered cardiac contractile function in mouse models of hypertrophy and heart failure. Nevertheless, it never demonstrated clinically relev

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