Evaluation of carcinoembryonic antigen, tissue polypeptide antigen, placental alkaline phosphatase, and modified nucleosides as biological markers in malignant lymphomas.

摘要: Elevated levels of biological markers for cancer in various body fluids can play a role diagnosis and assessment response to treatment. In recent years several new substances have been evaluated as markers. The usefulness carcinoembryonic antigen (CEA) marker the gastrointestinal tract well other malignant conditions has established (Bacchus 1977). However, are still process evaluation. Modified nucleosides urine different types cancer, some positive correlations observed by Waalkes Borek (1975), Schoch Heller-Schoch (1977), Gehrke et al. (1979). During these early studies analytical methods used were cumbersome not suitable routine analysis. with development high-performance liquid chromatography (HPLC), fast great precision presented (Gehrke 1978), more extensive study clinical use modified therefore be performed. Tissue polypeptide (TPA) placental alkaline phosphatase (PLAP) proteins serum which may serve diseases (Bjorklund 1980; Holmgren 1978). aim present was evaluate above-mentioned tumor individually together relation burden stage disease series 63 patients three kinds lymphoma. assessed this below detail.