Rheumatoid arthritis, spondyloarthropathies, and relapsing polychondritis.

摘要: The neurologic complications of rheumatic disease are highly variable and their manifestations linked to the pathogenesis clinical phenotype specific rheumatologic syndrome. In active rheumatoid arthritis (RA), peripheral nervous system is most commonly involved mononeuritis multiplex, nerve entrapment vascultitic sensorimotor neuropathy not uncommon. Central such as pachymeningitis cerebral vasculitis rare. TNF blockade therapy RA rarely associated with demyelinating syndromes. spondyloarthropathies, especially ankylosing spondylitis (AS), more frequent in long-standing, advanced include atlantoaxial subluxation, cauda equina syndrome, spinal stenosis, acute vertebral fractures. Peripheral involvement any spondyloarthropaties Relapsing polychondritis (RP) characterized by recurring bouts inflammation, destruction cartilaginous structures, systemic central vasculitis. Visual-oculo auditory common. Definitive treatment prevention subsequent ones dependent upon effective RA, AS or RP.