Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol
作者： Stephen G. Davies , David S. Hewings , Wataru Kurosawa , James A. Lee , Paul M. Roberts
DOI: 10.1007/S10870-013-0479-X
关键词:
摘要: 3-(N-Methylamino)cyclohexane-1,2-diols (RS,RS,RS)-25 and (1RS,2RS,3SR)-26 were synthesised their crystal structures studied by X-ray diffraction. Compound 25 co-crystallizes with chloroform in the orthorhombic space group Pna2 1 cell parameters of a = 11.8550(2) A, b = 19.8293(4) A, c = 10.6163(2) A, V = 2495.64(8) A3 Z = 8. 26 crystallizes triclinic P–1 a = 13.1019(3) A, b = 15.0122(3) A, c = 18.5562(5) A, α = 95.3082(8)°, β = 90.3738(10)°, γ = 115.2775(9)°, V = 3281.87(14) A3 Z = 16. Both characterised arrays hydrogen bonding interactions. (RS,RS,RS)-3-(N-Methylamino)cyclohexane-1,2-diol (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol
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sci-hub.se 参考文章(24)
Kristína Csatayová, Stephen G. Davies, James A. Lee, Kenneth B. Ling, Paul M. Roberts, Angela J. Russell, James E. Thomson, Syntheses of trans-SCH-A and cis-SCH-A via a Stereodivergent Cyclopropanation Protocol Organic Letters. ,vol. 12, pp. 3152- 3155 ,(2010) , 10.1021/OL101295T
Amber L. Thompson, David J. Watkin, CRYSTALS enhancements: absolute structure determination Journal of Applied Crystallography. ,vol. 44, pp. 1017- 1022 ,(2011) , 10.1107/S0021889811034066
A. Altomare, G. Cascarano, C. Giacovazzo, A. Guagliardi, M. C. Burla, G. Polidori, M. Camalli, SIR92 – a program for automatic solution of crystal structures by direct methods Journal of Applied Crystallography. ,vol. 27, pp. 435- 435 ,(1994) , 10.1107/S002188989400021X
Caroline Aciro, Timothy D. W. Claridge, Stephen G. Davies, Paul M. Roberts, Angela J. Russell, James E. Thomson, Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol Organic and Biomolecular Chemistry. ,vol. 6, pp. 3751- 3761 ,(2008) , 10.1039/B808811J
J. Cosier, A. M. Glazer, A nitrogen‐gas‐stream cryostat for general X‐ray diffraction studies Journal of Applied Crystallography. ,vol. 19, pp. 105- 107 ,(1986) , 10.1107/S0021889886089835
Caroline Aciro, Stephen G. Davies, Wataru Kurosawa, Paul M. Roberts, Angela J. Russell, James E. Thomson, Highly Diastereoselective anti-Dihydroxylation of 3-N,N-Dibenzylaminocyclohex-1-ene N-Oxide Organic Letters. ,vol. 11, pp. 1333- 1336 ,(2009) , 10.1021/OL900114B
Stephen G. Davies, Kenneth B. Ling, Paul M. Roberts, Angela J. Russell, James E. Thomson, Philip A. Woods, The stereodivergent aziridination of allylic carbamates, amides and sulfonamides Tetrahedron. ,vol. 66, pp. 6806- 6813 ,(2010) , 10.1016/J.TET.2010.06.059
Caroline Aciro, Stephen G. Davies, Paul M. Roberts, Angela J. Russell, Andrew D. Smith, James E. Thomson, Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. Organic and Biomolecular Chemistry. ,vol. 6, pp. 3762- 3770 ,(2008) , 10.1039/B808812H
Sharan K. Bagal, Stephen G. Davies, Ai M. Fletcher, James A. Lee, Paul M. Roberts, Philip M. Scott, James E. Thomson, Concise and highly selective asymmetric synthesis of acosamine from sorbic acid Tetrahedron Letters. ,vol. 52, pp. 2216- 2220 ,(2011) , 10.1016/J.TETLET.2010.12.035
Kristína Csatayová, Stephen G. Davies, James A. Lee, Kenneth B. Ling, Paul M. Roberts, Angela J. Russell, James E. Thomson, Chemo- and diastereoselective cyclopropanation of allylic amines and carbamates Tetrahedron. ,vol. 66, pp. 8420- 8440 ,(2010) , 10.1016/J.TET.2010.08.055