The stereodivergent aziridination of allylic carbamates, amides and sulfonamides
作者： Stephen G. Davies , Kenneth B. Ling , Paul M. Roberts , Angela J. Russell , James E. Thomson
DOI: 10.1016/J.TET.2010.06.059
关键词: Amine gas treating 、 Carboxamide 、 Stereochemistry 、 Amine derivatives 、 Sulfonamide 、 Chemistry 、 Protecting group 、 Steric effects 、 Allylic rearrangement 、 Aziridine
摘要: A stereodivergent protocol for the aziridination of a range cyclic allylic amine derivatives has been developed. syn-Products can be obtained in >99:1 dr under H-bonded control and anti-products are steric by judicious choice N-protecting groups.
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