A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.
作者： M. Dasso , T. Seki , Y. Azuma , T. Ohba , T. Nishimoto
DOI: 10.1002/J.1460-2075.1994.TB06911.X
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摘要: … RCC1 by circumventing the requirement for RCC I as in our experiments, or simply by stabilizing the mutant proteins. Together, these results imply that RCC l's primary activity in nuclear …
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