Structural--functional relationships in experimentally induced brain damage.

作者: Patricia M. Rodier

DOI: 10.1016/S0079-6123(08)60514-2

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摘要: Publisher Summary The purpose of this chapter is to introduce some the themes neuroteratology by tracing its historical connections study somatic malformations. This most easily done discussing studies general teratogens, that is, ones which affect all cells. Antimitotic agents are a classic example teratogens with effects. availability antisera growth hormone, hormone releasing factor (GHRF) and somatostatin, fact feedback loops system do not automatically adjust levels normal, target tissue includes or parts body. pattern in absence distinctive. In mouse rat, growthhormone-deficient animals begin diverge from normal after about two weeks postnatal life, as seen mutants such dwarf mouse, lacks somatotropes. One teratological syndrome appears exhibit fetal alcohol (FAS).

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