作者: John I. Pitt , Lene Lange , Alastair E. Lacey , Daniel Vuong , David J. Midgley
DOI: 10.1371/JOURNAL.PONE.0170254
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摘要: Aspergillus hancockii sp. nov., classified in subgenus Circumdati section Flavi, was originally isolated from soil peanut fields near Kumbia, the South Burnett region of southeast Queensland, Australia, and has since been found occasionally other substrates locations Australia. It is phylogenetically phenotypically related most closely to A. leporis States M. Chr., but differs conidial colour, minor features particularly metabolite profile. When cultivated on rice as an optimal substrate, produced extensive array 69 secondary metabolites. Eleven 15 abundant metabolites, constituting 90% total area under curve HPLC trace crude extract, were novel. The genome hancockii, approximately 40 Mbp, sequenced mined for genes encoding carbohydrate degrading enzymes identified presence more than 370 114 gene clusters, demonstrating that capacity degrade cellulose, hemicellulose, lignin, pectin, starch, chitin, cutin fructan nutrient sources. Like species, exhibited a diverse profile, 26 polyketide synthase, 16 nonribosomal peptide synthase synthase-like enzymes.